5-Methyl-CTP

5-Methyl-CTP

Author: ApexBio

purity:

≥ 95% by AX-HPLC

shortsummary:

A CTP analogue used for in vitro mRNA synthesis

Protease Inhibitor Cocktail

Synonyms:

5-Methylcytidine-5'-Triphosphate, 5-Me-CTP, 5mCTP, 5-mCTP

Concanavalin A Solution

Formula:

C10H18N3O14P3 (free acid)

M.Wt:

497.1 (free acid)

SMILES:

[NH2]=C(C(C)=CN1C2C(O)C(O)C(COP([O-])(OP([O-])(OP([O-])([O-])=O)=O)=O)O2)=NC1=O.[Li+].[Li+].[Li+].[Li+]

Storage:

Store at -20°C or below

Physical Appearance:

Solution

DeliveryTime:

In stock

protease and phosphatase inhibitor cocktail

ShippingType:

Dry ice

description:

5-Methyl-CTP is a modified nucleoside triphosphate, commonly used to substitute the naturally occurring cytidine triphosphate (CTP) during in vitro mRNA synthesis. Methylation of the cytosine C-5 position is a common, post-transcriptional modification for mRNA. Incorporation of chemically modified 5-methyl-CTP can increase mRNA stability and protein expression, and meanwhile, reduce interaction of innate immune receptors with in vitro-transcribed (IVT) mRNA. Apart from its application in encoding antigens for the activation of immune response against a variety of diseases such as COVID-19, IVT mRNA can also express the nanobody/variable domain of heavy chain of heavy-chain antibody targeting the intracellular components, enabling intracellular antigen labeling and manipulation.

related websites:

APExBIO Technology LLC is a premier provider of Small Molecule Inhibitors/Activators, Compound Libraries, Peptides, Assay Kits, Fluorescent Labels, Enzymes, Modified Nucleotides, mRNA synthesis and various tools for Molecular Biology. We carry a broad product line in over 7142 different research areas such as cancer, immunology, neurosciences, apoptosis and epigenetics etc. Based in USA (Houston, Texas), we have been serving the needs of customers across the world.